张大同
发布时间: 2014-10-17   浏览次数: 1856      

 

姓  名

张大同

性  别

出生年月

1973.04

学  历

博士

毕业时间

 2006.06

专  业

药物化学、有机化学

电  话

 13708925788

邮  编

250353

E-MAIL

 datong_zhang@163.com

单  位

化学与制药工程学院

通讯地址

济南市长清区大学路3501号 齐鲁工业大学化工学院

个人简历:

1991.9-1995.7,山东医科大学 药学专业 本科;

1995.9-1998.7,山东医科大学 药物化学专业 硕士;

2003.09-2006.7,山东大学 有机化学专业 博士;

2006.7至今,齐鲁工业大学化学与制药工程学院任教。制药工程与药物制剂系教授,硕士研究生导师。

2012.7-2013.1,美国Virginia Commonwealth University 访问学者

研究领域: 

药物化学、有机分子荧光探针。

奖励和荣誉:

2007年指导的论文被评为“校级优秀本科毕业论文”

2008年指导的论文被评为“校级优秀本科毕业论文”

2009年指导的论文被评为“校级优秀本科毕业论文”

2012年指导的论文被评为“校级优秀本科毕业论文”

2008年指导的论文被评为2009年“山东省优秀学士学位论文” 

2011年被评为山东轻工业学院优秀教师.

2014年 “有机废弃物发酵和可燃气体输送发电监控关键技术研究”获山东省科技进步二等奖(第三名)

发表文章:
1. Xiao-Bo Wang, Xue Hao, Datong  Zhang*,  Yan  Jiang. Reaction-based Fluorescent Turn-on Probe for Selective Detection of  Thiophenols in Aqueous Solution and Living Cell. Dyes and Pigments, 2017, 142,  167-174 .
2. Xiao-Bo Wang,
Datong   Zhang*. A novel  reaction-based fluorescent turn-on probe for biothiols and its application in  cell imaging. Sensors and Actuators B: Chemical, 241 (2017)  327–334.
3.  Xiao-Bo Wang, Jianhua Zhou, Datong   Zhang and Bin Wang.  A very fast 3-hydroxy-coumarin-based fluorescent probe for highly selective and  sensitive detection of thiophenols and its application in water samples. Anal.  Methods, 2016, 8,  6916–6922.
4.  Ruibing An, Peng Wei, Datong   Zhang*, Na Su. A  highly selective 7-hydroxy-3-methyl-benzoxazinone based fluorescent probe for  instant detection of thiophenols in environmental samples. Tetrahedron Letters,  2016, 57,  3039-3042.
5. Ruibing  An,   Datong   Zhang,*,  Yan  Chen,  Yue-zhi   Cui. A “turn-on” fluorescent and colorimetric sensor     for selective 
detection  of Cu2+ in aqueous  media  and  living  cells. Sensors and Actuators B: Chemical,  222 (2016) 48–54.
6.  Peng Wei, Datong  Zhang*,  Zhigang Gao, Wenqing Cai, Weiren Xu, Lida Tang, Guilong Zhao*. Iodine  Monochloride  (ICl) as a Highly Efficient, Green Oxidant for the Oxidation of Alcohols to  Corresponding Carbonyl  Compounds. Synthetic Commun.,
 2015, 45(12):1457-1470.
7.  
Datong  Zhang*, Yuntong  Ma, Ruibing An. New colorimetric chemosensor based on rhodamine hydrazide to  detect Cu2+ ions by naked eye. Res Chem Intermed., 2015, 41(8):  5059-5069.
8.  
Gao  Zhigang, Zhang Datong*,  Wei Peng, Wang Zhe, Xie Yafei, Liu Yuqiang, Xu Weiren, Tang Lida, Zhao Guilong*.  A facile convergent synthetic procedure for 3-deoxydapagliflozin as SGLT2  inhibitor. Chin. J. Org. Chem, 2014, 34, 1829-1939..
9.  
Datong  Zhang, Yuntong Ma, Yu Liu and Zhao-Peng Liu.  Synthesis of sulfonylhydrazone- and acylhydrazone- substituted   8-ethoxy-3-nitro-2H-chromenes as potent antiproliferative and apoptosis inducing  agents. Arch. Pharm. Life Sci. 2014, 347,  576-588.

10
. Datong  Zhang*, Lingyan Huo, Laichun Lu, Qiong Yu, Jianwu  Wang, Yanyan Yang. Synthesis and preliminary antibacterial evaluation of  hydroxamic acid and N-formyl hydroxylamine derivatives bearing oxazole ring.  Medicinal Chemistry Research, 2013, 22(3):1426-1437.
11.  
Datong  Zhang*, Guangtian Wang, Guilong Zhao,Weiren Xu, Lingyan Huo. Synthesis  and Cytotoxic Activity of Novel   3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives .  European Journal of Medicinal Chemistry, 2011,46  (12):5868-5877.
12.
Datong Zhang*, Guangtian Wang, Chubing Tan*,  Weiren Xu,  Yuan Pei and Lingyan Huo. Synthesis and biological evaluation of  3-(1H-indol-3-yl)pyrazole-5-carboxylic acid derivatives. Archives  of Pharmacal research, 2011,  34(3):343-355.  
13.Datong Zhang*, Jiong Jia, Lijuan Meng, Weiren Xu, Lida  Tang, and Jianwu Wang. Synthesis and Preliminary Antibacterial Evaluation of  2-Butyl Succinate-based Hydroxamate Derivatives Containing Isoxazole Rings.  Archives of Pharmacal research, 2010,  33(6):831-842.
14. Datong Zhang, Zongheng Wang, Weiren  Xu, Fanggang Sun, and Jianwu Wang. Design,Synthesis and Antibacterial Activity  of Novel Actinonin Derivatives Containing Benzimidazole Heterocycles.  European Journal of Medicinal Chemistry, 2009,44 (5),2202-2210

目前承担和参与项目:
先后主持和参与了山东省自然科学基金、山东省中青年科学家奖励基金和济南市高校院所自主创新计划,并承担多项企事业单位横向课题。

社会兼职:中国化学会会员。现为Bioorganic & medicinal chemistry letter、European journal of medicinal chemistry、Journal of heterocyclic chemistry, Medicinal Chemistry Research等期刊审稿专家。

 

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